Zebra · Desktop barcode label printer

Zebra ZD421 4-inch Desktop Label Printer

A 4-inch desktop label printer in direct thermal, thermal transfer and ribbon-cartridge versions, for shipping, product, shelf and hospital labels where a GK420 or ZD420 used to sit.

Print method
Thermal transfer · direct thermal
Resolution
203 or 300 dpi
Print width
Up to 104 mm (4.09 in.)
Speed
Up to 152 mm/s (6 ips)
Ribbon
300 m or 74 m roll · 74 m cartridge
Connectivity
USB · USB Host; Wi-Fi, Ethernet optional

ZD421 price in India: ask our team for today's competitive price. Share your requirement and budget, and we will help you choose the right configuration and send a written quotation with current pricing and delivery time.

Covered by the manufacturer's warranty. The warranty period, terms and conditions are as declared by Zebra.

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Zebra ZD421 4-inch desktop barcode label printer

Why the ZD421

4-inch desktop labels now, the network added later

The ZD421 is Zebra's current 4-inch desktop in the ZD400 Series and the model Zebra names on its GK420 and ZD420 support pages as their replacement. It runs Link-OS and comes in direct thermal, thermal transfer (ribbon roll) and thermal transfer (ribbon cartridge) versions.

Three print versions

Direct thermal needs no ribbon. The thermal transfer roll model takes 300 m or 74 m ribbons. The cartridge model takes a 74 m ribbon cartridge that loads in one direction only, which makes ribbon changes simpler.

Add the network later

USB 2.0 and USB Host are standard, with Bluetooth Low Energy for the setup app. Ethernet 10/100, Wi-Fi 6 with Bluetooth 5.3 and Wi-Fi 5 with Bluetooth 4.1 can be fitted at the factory or in the field, and RS-232 serial in the field, so a USB printer bought today can join the network later.

Keeps your label formats

It understands ZPL II, EPL 2, XML, ZBI and PDF Direct, the same Zebra languages used by GK420 and ZD420 fleets. Test your existing formats once before you switch the whole fleet.

A healthcare version

The ZD421-HC has a white housing, disinfectant-ready plastics, a sealed button panel, UV-resistant housing and an IEC 60601-1 certified power supply, for specimen, pharmacy and wristband labels.

Wide range of media

Rolls up to 127 mm outside diameter on 12.7 mm or 25.4 mm cores (38.1, 50.8 and 76.2 mm with adapters). It prints labels, tags, receipt paper and wristbands, with a field-fit peeler or cutter.

Managed from one place

The ZD421 works with Zebra DNA (formerly Print DNA). PrintSecure sets up secure connections, and Printer Profile Manager Enterprise, a separately licensed tool, manages a networked fleet from one place. ZebraDesigner Essentials label software is a free download.

Used in

  • Retail and FMCG
  • Warehousing and 3PL
  • E-commerce and courier
  • Auto-component and electronics plants
  • Hospitals and pharmacies
  • Packaged-goods units (MRP and net-quantity labels)

For buyers in India

Using the ZD421 in India

These are the points buyers in India ask us about the ZD421. Mention the ones that apply to you when you request a quote.

Prints a 4 × 6 inch courier label in about a second

The ZD421 prints a 4 × 6 inch (101.6 × 152.4 mm) courier label in about one second at 152 mm/s (6 ips). It prints up to 104 mm wide at 203 dpi and takes direct thermal media up to 108 mm wide, so the label fits. A full 127 mm roll on a 25.4 mm core holds about 64 m even at the thickest 0.19 mm media, or roughly 410 labels with a 3 mm gap.

MRP and net-quantity text at 203 or 300 dpi

The ZD421 prints MRP and net-quantity text at 203 or 300 dpi; check the height of the printed digit, not the font size setting. Ask us to set up your label format and print test labels on your roll.

Hindi and Tamil need a loaded font or an image

To print Hindi, Tamil or another Indian script on the ZD421, load a licensed font for that script on the printer, or have the label software send the text as an image. Zebra describes the ZD421 as Unicode compliant with native OpenType font support. Its ZPL guide documents character shaping (^PA) and complex text layout (^TB) on firmware V60.14 or later, which scripts such as Devanagari need. Zebra's international font packs list Arabic, Thai, Chinese, Japanese and Korean, but no Indian script. Approve a printed proof before rollout. Ask us to set up your label format and print test labels on your roll.

ZD421-HC prints wristbands and larger pharmacy labels

Use the ZD421-HC for patient wristbands as well as specimen and pharmacy labels. Its 4-inch print width also covers larger pharmacy labels that a 2-inch printer cannot.

Keep it under 41 °C on a steady mains supply

Run the ZD421 in a room under 41 °C, and use a stabiliser or online UPS where mains runs high. Zebra rates it to run between 4.4 °C and 41 °C, on a supply rated 100-240 VAC, 50-60 Hz.

Specifications

Zebra ZD421 technical specifications

Zebra ZD421 specifications
General
Versions Direct thermal; thermal transfer (ribbon roll); thermal transfer (ribbon cartridge); healthcare model ZD421-HC
Operating system Link-OS
Memory 512 MB Flash, 256 MB SDRAM (64 MB user non-volatile, 8 MB user SDRAM)
Printer languages ZPL II, EPL 2, XML, ZBI, PDF Direct
Software Zebra DNA: PrintSecure; Printer Profile Manager Enterprise (licensed separately); printer setup app over Bluetooth Low Energy; ZebraDesigner Essentials (free download)
Printing
Resolution 203 dpi (8 dots/mm); 300 dpi (12 dots/mm) optional
Maximum print width 104 mm (4.09 in.) at 203 dpi; 106 mm (4.16 in.) at 300 dpi (cartridge model: 104 mm at both)
Maximum print speed 152 mm/s (6 ips) at 203 dpi; 102 mm/s (4 ips) at 300 dpi
Media sensors Full-width movable reflective/black-mark sensor; multi-position transmissive/gap sensor
Fonts 16 expandable ZPL II bitmap fonts, 2 scalable ZPL fonts, 5 expandable EPL2 fonts, native OpenType support
Barcodes 1D: Code 11, 39, 93, 128, ISBT-128, UPC-A/E, EAN-8/13, Codabar, MSI, Plessey, 2-of-5 and others. 2D: PDF417, MicroPDF, Data Matrix, QR Code, Aztec, MaxiCode, Codablock, Code 49
Media
Media width 15-108 mm (direct thermal); 15-112 mm (ribbon roll); 15-118 mm (cartridge)
Label length 6.35-991 mm (0.25-39 in.)
Maximum roll diameter 127 mm (5 in.) outside diameter
Core size 12.7 mm and 25.4 mm standard; 38.1, 50.8 and 76.2 mm with optional adapters
Media thickness 0.08-0.19 mm
Media types Roll or fan-fold; die-cut or continuous labels with or without black mark; tags; receipt paper; wristbands
Ribbon (roll model) 300 m (66 mm OD, 25.4 mm core, 1:4 media-to-ribbon) or 74 m (34 mm OD, 12.7 mm core, 1:1); width 33.8-109.2 mm
Ribbon (cartridge model) 74 m cartridge, 109.2 mm wide
Media handling Tear-off standard; dispenser/peeler with label-present sensor and cutter optional (field installable). The cutter cuts continuous paper, linered label and tag stock up to 0.19 mm, not through labels and liner
Connectivity
Standard USB 2.0, USB Host; Bluetooth Low Energy for the Zebra printer setup app only
Optional Factory or field installed: Ethernet 10/100; Wi-Fi 6 (802.11ax) with Bluetooth 5.3 (MIMO factory, SISO field); Wi-Fi 5 (802.11ac) with Bluetooth 4.1. Field installed: RS-232 serial (auto-sensing, DB-9)
Mobile and desktop OS Windows, Android, iOS
Physical and environment
Dimensions (L × W × H) Direct thermal 220.8 × 177.5 × 150.7 mm; ribbon roll 267 × 202 × 189 mm; cartridge 254 × 202 × 177 mm
Weight Direct thermal 1.35 kg; ribbon roll 2.05 kg; cartridge 2.3 kg
Operating temperature 4.4 °C to 41 °C
Storage temperature -40 °C to 60 °C
Humidity 10-90% operating, 5-95% storage, non-condensing
Power Auto-detecting 100-240 VAC, 50-60 Hz; ENERGY STAR; optional 2,750 mAh battery
Healthcare model (ZD421-HC) White housing, disinfectant-ready plastics, sealed buttons, UV-resistant housing, IEC 60601-1 certified power supply
Warranty
Warranty Covered by the manufacturer's warranty. The warranty period, terms and conditions are as declared by Zebra.

Optional accessories

  • Dispenser/peeler with label-present sensor
  • Cutter
  • Ethernet 10/100 module
  • Wi-Fi and Bluetooth module
  • RS-232 serial module
  • Media core adapters (38.1, 50.8, 76.2 mm)
  • 2,750 mAh battery and carrying case (the case does not fit with a cutter or peeler)
  • Attached power supply for cord-free installation
  • ZKDU keyboard display unit
  • Mounting adapter bracket for a GK420 or LP/TLP 2824 position

Ask for labels, ribbons and any connectivity module in the same quotation.

Specifications from Zebra's published documents, last checked 13 October 2026. Makers can change specifications without notice; we confirm the exact model and configuration in your written quotation. About our product information

Compare

ZD421 or another model?

Zebra ZD421 compared with similar models
Feature Zebra ZD421 Zebra ZD230 Zebra ZD621
Resolution 203 or 300 dpi 203 dpi 203 or 300 dpi
Maximum print speed 152 mm/s (6 ips) at 203 dpi 152 mm/s (6 ips) 203 mm/s (8 ips) at 203 dpi
Ribbon 300 m or 74 m roll; 74 m cartridge 300 m or 74 m roll (ZD230t) 300 m or 74 m roll
Standard ports USB 2.0, USB Host USB 2.0 Ethernet, USB 2.0, USB Host, serial
Memory 512 MB Flash, 256 MB SDRAM 128 MB Flash, 128 MB SDRAM 512 MB Flash, 256 MB SDRAM
Best for Mid-range desktop labelling with room to add Wi-Fi or Ethernet Basic 203 dpi labelling Premium desktop with Ethernet and serial built in

Exploring for a different use?

If your job differs from what the ZD421 is built for, these Zebra models may fit it better:

  • Buyers who run a busy labelling desk on the network and want Ethernet and serial built in often look at the Zebra ZD621 (up to 203 mm/s (8 ips), Ethernet and serial standard).
  • Buyers who only need 203 dpi labels over USB often look at the Zebra ZD230 (203 dpi, up to 152 mm/s, USB).
  • Buyers who print labels 56 mm wide or narrower on a tight desk often look at the Zebra ZD411 (2-inch printer, body 115 mm wide in the direct thermal model).

Not sure which one fits? Tell us how you will use it and we will recommend a model.

Part numbers

Zebra part numbers for the ZD421

Quote the part number for your ZD421 in your enquiry and we confirm the exact part. These are Zebra's own codes; if you do not have yours, send a photo of the device's rating label.

Printheads

Printheads for the Zebra ZD421
Part number What it is Ask about this part
P1112640-019 Printhead, 203 dpi, ZD421 direct thermal Ask on WhatsApp about P1112640-019 (opens in a new tab)
P1112640-020 Printhead, 300 dpi, ZD421 direct thermal Ask on WhatsApp about P1112640-020 (opens in a new tab)
P1112640-026 Printhead, 203 dpi, ZD421 direct thermal healthcare (white) Ask on WhatsApp about P1112640-026 (opens in a new tab)
P1112640-027 Printhead, 300 dpi, ZD421 direct thermal healthcare (white) Ask on WhatsApp about P1112640-027 (opens in a new tab)
P1112640-218 Printhead, 203 dpi, ZD421 thermal transfer Ask on WhatsApp about P1112640-218 (opens in a new tab)
P1112640-219 Printhead, 300 dpi, ZD421 thermal transfer Ask on WhatsApp about P1112640-219 (opens in a new tab)
P1116110-009 Printhead, 203 dpi, ZD421 ribbon cartridge Ask on WhatsApp about P1116110-009 (opens in a new tab)
P1116110-010 Printhead, 300 dpi, ZD421 ribbon cartridge Ask on WhatsApp about P1116110-010 (opens in a new tab)

Platen rollers and spares

Platen rollers and spares for the Zebra ZD421
Part number What it is Ask about this part
P1112640-217 Platen Roller 300dpi Ask on WhatsApp about P1112640-217 (opens in a new tab)

Spare parts and upgrade kits

Spare parts and upgrade kits for the Zebra ZD421
Part number What it is Ask about this part
P1112640-015 Ethernet Module Ask on WhatsApp about P1112640-015 (opens in a new tab)
P1112640-017C Wireless Module, WiFi 802.11ac, MFI 3.0, Bluetooth 4.1, for all countries except USA, Canada and Japan Ask on WhatsApp about P1112640-017C (opens in a new tab)
P1112640-239C WiFi 802.11ac Wireless Module for all countries except USA, Canada and Japan Ask on WhatsApp about P1112640-239C (opens in a new tab)

Printheads for every printer we sell · Is it the printhead? Symptoms, tests and when to replace

Part numbers as published by Zebra, checked in Zebra's published documents on 10 October 2026. Parts and printer configurations available in India can change; we confirm the exact code and the delivery time in your quotation. About our product information

Request a quote for parts for the Zebra ZD421

Downloads

Datasheet and documents

Questions buyers ask

ZD421 FAQ

What is the price of the Zebra ZD421 in India?

The ZD421 price depends on the resolution you choose (203 or 300 dpi), the options you add and the quantity. We can quote the labels and ribbon with it. Ask our team for today's competitive price: share your requirement and budget, and we will help you choose the right configuration and send a written quotation with current pricing and delivery time.

We use a GK420 or ZD420. Should we move to the ZD421?

Zebra's support pages show that the GK420 and the ZD420 were last sold in Asia-Pacific on 31 December 2021 and that their support ended there on 28 February 2025. Both pages name the ZD421 as the replacement. The ZD421 keeps the 4-inch width and the ZPL and EPL languages, so most label formats carry over. Include one of your current labels when you ask for a quote.

Direct thermal, ribbon roll or ribbon cartridge: which ZD421 do we need?

Direct thermal prints on heat-sensitive labels and needs no ribbon, which suits shipping labels and receipts. The thermal transfer models print through a ribbon, which lets you use a wider range of label materials. The roll model takes 300 m or 74 m ribbons; the cartridge model takes a 74 m cartridge that loads in one direction only. Describe your labels when you ask for a quote.

Is there a version for hospitals?

Yes. Zebra lists a ZD421-HC healthcare model. It has a white housing, plastics designed for disinfectant wipes, a sealed button panel, a UV-resistant housing and an IEC 60601-1 certified power supply. It prints specimen labels, pharmacy labels and wristbands. If you print wristbands, mention the band type when you ask for a quote.

Can the ZD421 print over Wi-Fi or Ethernet?

Not out of the box. The standard printer connects over USB, and its Bluetooth Low Energy is only for Zebra's setup app. Ethernet or Wi-Fi can be fitted at the factory or added later as a field-installable module, and RS-232 serial in the field, so a USB printer can join your network when you need it.

Which ZD421 suits courier and e-commerce labels in India?

The direct thermal model. It needs no ribbon, prints up to 104 mm wide and takes media up to 108 mm wide, so a 4 × 6 inch (101.6 × 152.4 mm) shipping label fits. If the same printer must also make long-life product or asset labels, choose a thermal transfer model, which prints in both modes.

Can Allmark install the ZD421 and connect it to our software?

Yes. We install the ZD421 at your site, connect it so your ERP, warehouse or billing software prints to it (our own warehouse management system included) and train the people who use it. Tell us the software when you ask for a quote, and we include the setup in the quotation.

Get a written ZD421 quote with labels and setup

Send your label size, how many labels you print a day and the software you print from; we reply with a written quotation.

Since 2014 · 2000+ customers · 75,000+ devices installed · On-site installation & training · Software & ERP integration